1, 2, 4-trioxanes: New Trends in Malaria Chemotherapy

Natural products are the most important source of traditional medicine and have played a major role in the discovery of leads for the development of drugs to treat human diseases. Quinine, artemisinin, licochalcone A and tazopsine are examples of plant-derived natural products which have revealed antimalarial potency that give the important pharmacophore for the drug development. Many researchers focusing 1,2,4-trioxanes as an active pharmacophore from artemisinin as a lead for the development of new drug like molecules.