Biomedical Frontiers in Fluorine Chemistry

Reviews recent research on fluorine-containing, biologically relevant molecules in biology and medicinal chemistry. The text reports applications of bioactive organofluorine compounds as enzyme inhibitors, antithrombotics, anticancer agents, antiviral agents, antibacterials, central nervous system agents and antifungals and antimalarial agents. It also discusses the use of fluorine-containing amino acids as probes for investigating biomedical problems, including applications in fluorine-19 NMR, neurotransmission investigations, and fluorine-18 labelled tracers for positron emission tomography.